By C K Cain
ANNUAL stories IN MED CHEMISTRY V3 PPR.
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Extra resources for Annual Reports in Medicinal Chemistry, 3
The opportunity to develop novel psychoactive steroids remains a challenge to medicinal chemists. Pr OiY lNb Y4 O i r 18 (A-10749) - 19 iprindole m i n d o l eR 20 protript line yivacti1'- 11. CENTRAL STIMULANTS Chemistry In contrast to the efforts in the field of antidepressants, relatively little work on central stimulants was reported. The structureactivity relationship of amphetamine derivatives was studied by a molecular orbital method 74. The greatest central stimulant effect was associated with those compounds having the lmest negative charge on the ring carbon atom ortho to the side-chain and with the lowest dipole moment arising from Chap.
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